Case Report: Adult Female Acne Managed With Isotretinoin (Accutane) in Katy & Houston, Texas

by: Dr. Caroline Vaughn


At Village Dermatology, we provide comprehensive care for patients with persistent and treatment-resistant acne. Isotretinoin (Accutane) remains one of the most effective options for moderate to severe acne, particularly when other therapies have failed.

Patient Background

A 41-year-old female returned for a follow-up visit for facial acne. She was initially evaluated on November 21, 2025, at which time she began isotretinoin 40 mg twice daily (80 mg total daily dose), taken with a fatty meal. She presented today for focused monitoring while continuing therapy.

Clinical Examination

A focused facial examination was performed with dermoscopy. Findings included:

  • Comedonal papules

  • Inflammatory papules and pustules

  • Two new acne breakouts involving the nose and cheek

Despite reaching her cumulative dose goal, the patient continued to experience mild active lesions.

The patient appeared well-developed, well-nourished, alert, and in no acute distress.

Treatment Course & Management Plan

The patient reported no significant side effects from isotretinoin therapy. Given the presence of new breakouts, the decision was made to continue isotretinoin at 80 mg daily to further improve disease control.

Key Treatment Details:

  • Medication: Isotretinoin 40 mg capsules

  • Dose: 40 mg twice daily

  • Month of Therapy: Month 5

  • Protocol: 1 mg/kg until cumulative dose of 200–220 mg/kg

A urine pregnancy test was performed in clinic and confirmed to be negative. The patient was successfully confirmed in iPledge, and her prescription was sent.

Isotretinoin Counseling & Monitoring

Extensive counseling was provided, including:

  • Use of two forms of contraception (secondary method: male vasectomy)

  • Monthly pregnancy testing and lab monitoring

  • Avoiding blood donation

  • Avoiding elective surgery for six months after treatment completion

  • Not sharing medication

  • Monitoring for side effects such as headaches, fatigue, abdominal pain, rash, or vision changes

The patient verbalized understanding of all risks and benefits.

Skin Care Recommendations

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To support treatment success, the patient was advised to use:

  • Non-comedogenic cleansers

  • Gentle moisturizers

  • Broad-spectrum sunscreen SPF 30+

She was counseled that improvement continues over time, with 60–80% improvement typically seen by 2–3 months, and further clearing expected as therapy continues.

Follow-Up

The patient will return in one month for continued isotretinoin monitoring and acne management.

Expert Acne & Accutane Treatment in Katy & Houston, Texas

At Village Dermatology, we specialize in adult acne treatment, including safe and closely monitored isotretinoin therapy. Our dermatologists provide personalized care to help patients achieve long-term acne control and prevent scarring.

📍 Serving Katy and Houston, Texas

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