Perioral Dermatitis in a Young Adult Female

by: Dr. Caroline Vaughn


A Dermatology Case Report from Village Dermatology in Katy & Houston, Texas

Case Overview

A 29-year-old female presented to Village Dermatology as a new patient with a chronic, itchy, red facial rash localized around the mouth and nose. The rash had been present for several months and was moderate in severity. She reported partial improvement with cephalexin, but noted that a previously prescribed oral steroid worsened the eruption.

This clinical pattern raised concern for perioral dermatitis, a common yet often misdiagnosed inflammatory facial condition.

Dermatologic Examination

A focused facial examination was performed using dermoscopy. The patient appeared well-developed, well-nourished, and in no acute distress.

Clinical findings included:

  • Erythematous papules around the perioral and perinasal areas

  • Associated itching and irritation

  • Absence of systemic symptoms

Based on the patient’s history and exam, the findings were most consistent with perioral dermatitis rather than acne or eczema.

Diagnosis: Perioral Dermatitis (L71.0)

Perioral dermatitis is a chronic inflammatory condition that commonly affects young women and is frequently triggered or exacerbated by:

  • Topical or oral steroids

  • Cosmetics and makeup

  • Fluorinated toothpaste

  • Sun, wind, and environmental exposure

In this case, steroid use likely contributed to worsening symptoms—a classic presentation.

Treatment Plan

Because the patient is currently breastfeeding, treatment options were carefully selected to ensure safety.

Prescribed Treatment

Topical Metronidazole 0.75% Cream (MetroCream®)

  • Apply to the entire face once to twice daily

Daily Skin Care Regimen

Morning

  1. Wash with a gentle cleanser

  2. Apply metronidazole cream

  3. Apply moisturizer with SPF 30+

Evening

  1. Wash with a gentle cleanser

  2. Apply metronidazole cream

  3. Apply moisturizer on top

Patient Counseling

  • Minimize cosmetics and facial products

  • Avoid topical steroids on the face

  • Use only non-comedogenic skincare products

  • Understand that perioral dermatitis is chronic and prone to flares

The patient was advised to contact the office if symptoms worsened or failed to improve.

Learn more

Coexisting Acne

The patient also exhibited comedonal and inflammatory acne. However, acne treatment will be deferred until the perioral dermatitis has resolved, as treating both simultaneously can worsen facial irritation.

Follow-Up

The patient will return in 1 month to assess response to treatment. If improvement is insufficient, topical tacrolimus may be considered.

Expert Facial Rash Care in Katy & Houston, Texas

At Village Dermatology, we specialize in diagnosing and treating complex facial rashes such as perioral dermatitis, acne, and inflammatory skin conditions. Proper diagnosis is essential—especially when steroid exposure complicates the presentation.

If you’re experiencing a persistent facial rash, our dermatology team proudly serves patients in Katy and Houston, TX with evidence-based, personalized care.

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