Botox, Xeomin, Daxxify, and Letybo: Which Wrinkle Relaxer Is Right for You?
At Village Dermatology Houston, we offer a wide range of injectable neuromodulators—Botox®, Xeomin®, Daxxify®, and Letybo®—to help reduce wrinkles, soften expression lines, and enhance your natural beauty. While most people are familiar with Botox, several newer options have emerged that offer distinct advantages for different patient needs.
Whether you're a first-time cosmetic patient or looking to switch up your regular treatment, our expert cosmetic consultants will work closely with you to select the best option based on your facial anatomy, treatment goals, and lifestyle. After a treatment with Botox®, the lines on your face that make you look angry or worried will soften, giving you a more relaxed, youthful appearance. With time and with consistent treatments, the lines eventually disappear, and many consider it to be a highly effective preventative procedure. Meet the Cosmetics Team at Village Dermatology in Memorial and Katy who believe in a natural, not frozen look.
đź’‰ What Do These Treatments Have in Common?
All four options—Botox, Xeomin, Daxxify, and Letybo—are FDA-approved botulinum toxin type A products. They work by temporarily relaxing specific facial muscles, smoothing the appearance of:
Forehead lines
Crow’s feet
Frown lines (glabellar lines)
Bunny lines
Other expression-related wrinkles
Although their mechanism of action is the same, they differ in formulation, onset, duration, and cost—and these nuances can help us personalize your results.
🧪 Botox®: The Gold Standard
Botox has been the household name in wrinkle relaxers for over two decades. It provides reliable, predictable results and typically lasts 3 to 4 months. It’s ideal for patients who:
Are new to cosmetic injectables
Want consistent results from a trusted brand
Have had good experiences with Botox in the past
✅ Why Choose Xeomin®?
Unique Feature: Naked (pure) botulinum toxin without accessory proteins.
Benefits:
Lower risk of antibody resistance: Ideal for long-term users or patients who’ve had diminishing results with Botox.
Great for sensitive skin: Fewer ingredients mean a lower chance of allergic reaction or immune interference.
Comparable results to Botox: Effects begin within 3–4 days and last about 3 months.
Best For: Patients wanting a “cleaner” formulation or who suspect Botox is no longer working as well.
✅ Why Choose Daxxify®?
Unique Feature: Peptide-enhanced formula for extended duration.
Benefits:
Longest-lasting neurotoxin: Results can last 6–9 months, compared to 3–4 months with others.
Fewer treatments per year: A convenient option for busy lifestyles.
FDA-approved for frown lines with excellent efficacy and safety data.
Best For: High-performance professionals or anyone looking for long-term results with minimal upkeep.
✅ Why Choose Letybo®?
Unique Feature: A Korean-developed botulinum toxin known for purity and natural results.
Benefits:
Soft, subtle effect: Especially effective for natural-looking results in the forehead and eye areas.
Great for first-timers: Gentle action and lower cost make it an appealing starting point.
High purity: Designed for precise diffusion and even results.
Best For: First-time cosmetic patients or anyone seeking a softer, more subtle enhancement.
🤔 Why Consider Alternatives to Botox?
ConcernAlternative BenefitBuilding resistance to BotoxXeomin: Reduced immune response riskWant fewer treatments per yearDaxxify: Longer-lasting resultsPrefer softer, natural outcomesLetybo: Gentle, smooth finishLooking for innovationDaxxify: Peptide-enhanced performanceCost-conscious choiceLetybo: More affordable option
👩‍⚕️ Personalized Consultations at Village Dermatology
Not sure where to start? Our cosmetic dermatology consultants will:
Review your treatment goals
Evaluate your skin and muscle movement
Consider your past experiences with injectables
Recommend the best neurotoxin for your individual needs
We serve patients in Houston, Katy, and Memorial, TX, with a reputation for precision results and a natural look.
đź“… Book Your Appointment Today
Start your wrinkle-smoothing journey with confidence. Whether you prefer the classic results of Botox or are curious about Daxxify, Xeomin, or Letybo, we’ll help you find the right solution. Contact us today to schedule your personalized consultation.
How Do Neuromodulator Injections Work?
The neuromodulator is injected into the muscle in areas of over-expression. Common areas include the frown lines between the brows, the forehead muscle, and the small muscles around the eye that cause crow's feet. Together, these areas help soften the appearance of the upper part of the face. Other areas that can be injected include lip flip, Nefertiti lift, gummy smiles, lip lines (often called smoker's lines, but we see them in singers and straw users as well), neck bands, and down-turned smiles. We also treat hands, feet, and under arms for excessive sweating, known as hyperhidrosis.
Procedure & Results
The procedure is simple and takes under 10 minutes to perform. There is minimal to no downtime following the procedure, and most patients return to work right away. Results can last up to 4 to 6 months, though individual results do vary. It is by far the cosmetic procedure with the highest patient satisfaction, and it is a wonderful yet simple way to invest in yourself. The result is a refreshed, restored, and rejuvenated you.
Before & After Case Studies
Moderate to Severe Crow’s Feet Lines
Before
After (Day 7)
Moderate to Severe Frown Lines
Before
After (Day 7)
Frequently Asked Questions about Botox
Our doctors, dermatologists and aestheticians and nurse injectors weigh in on common questions about use of the botulinum toxin, also known as Botox, for non-surgical injection.
Is Botox safe?
Absolutely, it is FDA-approved. To make sure that you are happy with the results of your treatment, it is vital to visit a trained professional. Botox is a medical procedure, and it should be treated as such. We are happy to discuss the best treatment plan with you to achieve your goals.
Botox is not indicated for those who are pregnant or breastfeeding.
What are the risks?
The most common risks are bruising and swelling. These can be mitigated if you see the right professional for the treatment.
Does it hurt?
Botox injections are done with a very small needle, roughly the same size and type as insulin shots. It is typically associated with minimal discomfort.
How long does it take to work?
Immediately after Botox injections, you may notice little bumps that look like mosquito bites. These will go away in ~ 20-30 minutes. Skin-smoothing effects will be noticeable as early as 3-5 days, but can take up to two weeks.
Does it make you look really different?
Botox smooths out your skin, but it does not fundamentally change your face or make you look like an Instagram filter, especially if done by a professional. People often comment that they look more rested.
Are the effects of Botox permanent?
Unfortunately, no. Over time, Botox is metabolized by the body. On average, one treatment typically lasts between 3-4 months. However, there are multiple factors that can cause this to vary. It depends on the individual, number of units injected, metabolism rate, and exercise frequency.
What happens after a Botox treatment?
There is no downtime after Botox. You can continue your regular skin-care routine. We do advise you to avoid excessive sweating/exercise for at least 4 hours post-treatment (the boost in circulation can spread the toxin to unwanted areas within the body). Avoid touching your face where you had the injections so that the Botox can properly settle. Avoid too much sun exposure to prevent bruising. Other than that, you are good to go!
If you are located in the Greater Houston area and have more questions about Botox, please contact us for more information.
What is the Science Behind Botox?
Under normal circumstances, a nerve comes into contact with a muscle at a neuromuscular junction. The nerve releases a neurotransmitter called acetylcholine. Acetylcholine travels to the muscle resulting in contraction of the muscle.
Botox keeps the neurotransmitter from stimulating the muscle, thereby keeping the muscle from contractin.
This is the reason that Botox® is helpful for "dynamic" wrinkles, or wrinkles that result from the contraction of muscles. With time and with repeated injections of Botox®, the muscles that produce unwanted wrinkles will become smaller, and this may result in treatments that last longer or in treatments that require few units of the toxin.