Refyne & DEFYNE

Hyaluronic acid dermal fillers designed to help support your skin while keeping you looking like you.

Restylane® Refyne and Defyne are designed with XpresHAn Technology™ to help soften laugh lines (nasolabial folds and marionette lines). This can help you restore a more natural look to your face while maintaining your facial expressions.1-4 So, you always look like you.

Although Restyane Defyne and Refyne are very similar, FDA-approved Defyne is a slightly firmer dermal filler. This makes it best suited for facial folds and lines that are very deep.

Restylane Refyne is similar to Defyne. However, the hyaluronic acid gel formulation in this product is a bit more flexible than that of Restylane Defyne. Refyne works best on folds and wrinkles that are relatively superficial.

Some patients benefit the most from using a combination of Restylane Defyne and Refyne.


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Various filler options, Filler pre-and post-care instructions.

Juvederm Voluma

Juvederm Volbella

Juvederm UltraXC and UltraPlusXC

Botox, Dysport and Xeomin


Refyne & Defyne